Michael Irwin, MD

  • Norman Cousins Professor, Department of Psychiatry and Biobehavioral Sciences, at the David Geffen School of Medicine, UCLA
  • Director, Cousins Center for Psychoneuroimmunology, UCLA Neuropsychiatric Institute
  • Vice Chair Elect, UCLA Collaborative Centers for Integrative Medicine
  • Member, UCLA’s Jonsson Comprehensive Cancer Center

Dr. Irwin is a member of the Advisory Council of the National Center for Complementary and Alternative Medicine and is immediate past president of the Psychoneuroimmunology (PNI) Research Society. He is current President-Elect of the Academy of Behavioral Medicine Research. Dr. Irwin is Associate Editor of the journal Brain, Behavior and Immunity and has recently served as Associate Editor of Psychosomatic Medicine. His principal research interests focus on the mechanisms of neuroimmune interactions and the impact of PNI processes on disease. Dr. Irwin’s program of research involves several ongoing collaborative projects including 1) evaluating the effects of depression on immunity with testing of specific immune responses to varicella zoster virus and assessment of herpes zoster risk in older adults; 2) determining the bi-directional interaction between disordered sleep and cytokines with an emphasis on alcohol abusing populations; 3) testing the impact of stress on neuroimmune mechanisms and progression of rheumatoid arthritis; 4) examining the ability of a behavioral intervention (Tai Chi Chih) to improve psychological adaptation, health functioning and augment baseline and vaccine-stimulated varicella zoster specific immunity in aging; 5) characterizing the effects of sympathetic mechanisms on pro-inflammatory and cellular adhesion molecule expression in cardiovascular disease patients.

Selected Publications

Jung W, Irwin M. Reduction of natural killer cytotoxic activity in major depression: an interaction between depression and cigarette smoking. Psychosomatic Medicine. 1999; 61:263-270

Irwin M, Miller C. Decreased natural killer cell responses and altered interleukin-6 and interleukin-10 production in alcoholism: an interaction between alcohol dependence and African-American ethnicity. Alcohol: Clinical Experience and Research. 2000; 24:560-569.

Redwine L, Hauger RL, Gillin JC, Irwin M. Effects of sleep and sleep deprivation on Interleukin-6, growth hormone, cortisol and melatonin levels in humans. Journal of Clinical Endocrinology and Metabolism. 2000; 85:3597-3603.

Redwine L, Dang J, Hall M, Irwin M. Disordered sleep, nocturnal cytokines and immunity in alcoholics. Psychosomatic Medicine. In press.

Contact Information

Michael Irwin, MD
Cousins Center for Psychoneuroimmunology
300 UCLA Medical Plaza
Suite 3109
Box 957076
Los Angeles, CA 90095
On-campus mail: 300 Med Plaza Suite 3109 707624
Tel: (310) 825-8281
Fax: (310) 794-9247
E-mail: mirwin1@ucla.edu

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